(06-02-15) Effect of increased intake of skimmed milk, casein, whey or water on body composition and leptin in overweight adolescents

Effect of increased intake of skimmed milk, casein, whey or water on body composition and leptin in overweight adolescents: a randomized trial.
Larnkjaer A1, Arnberg K, Michaelsen KF, Jensen SM, Mølgaard C.
Author information
Abstract
BACKGROUNDS:
Dairy proteins may support muscle protein synthesis and improve satiety in adults. However, there are limited studies using exact measures of body composition, especially in adolescents.
OBJECTIVES:
This study investigates the effect of milk proteins and water on body composition and leptin in overweight adolescents.
METHODS:
Subjects (n = 193) aged 12-15 years were randomized to drink 1 L d-1 of skimmed milk, whey, casein (all milk-based drinks 35 g protein L-1 ) or water for 12 weeks. Twenty participants dropped out. A pre-test control group of 32 adolescents was examined 12 weeks before start of intervention. Outcomes included leptin and dual-energy X-ray absorptiometry scanning. The effects of the milk-based drinks on body composition and leptin were compared with baseline, pre-test control and water.
RESULTS:
Lean mass index (LMI) increased compared to baseline (all 95% confidence intervals 0.05-0.50 kg m-2 , all P ≤ 0.009) and the pre-test control group (0.044-0.247 kg m-2 , P ≤ 0.002) for all four test drinks. Fat mass index (FMI) increased only for milk-based drink groups compared with baseline (0.15-0.67 kg m-2 , P < 0.001) and also compared with water (0.029-0.255 kg m-2 , P ≤ 0.011). For pre-test control, there was no change in FMI or LMI. Leptin increased in the casein (1.016-3.246 ng mL-1 , P < 0.001; 0.952-3.294 ng mL-1 , P < 0.001) and whey groups (0.135-2.273 ng mL-1 , P = 0.027; 0.069-2.322, P = 0.038) compared with water and pre-test control group, respectively.
CONCLUSIONS:
Although milk proteins increased LMI in overweight adolescents, there was a concurrent increase in FMI and leptin, whereas water only resulted in increased LMI. Thus, increased water intake may be beneficial for body composition in overweight adolescents.

Source: Pediatr Obes. 2015 Jan 22. doi: 10.1111/ijpo.12007. [Epub ahead of print]

News

---

In evidenza

"L'informazione presente nel sito serve a migliorare, e non a sostituire, il rapporto medico-paziente."

Per coloro che hanno problemi di salute si consiglia di consultare sempre il proprio medico curante.