(13-02-15) Combined inhalation and oral supplementation of Vitamin A and Vitamin D: A possible prevention and therapy for tuberculosis.

Authors
Syal K1, Chakraborty S2, Bhattacharyya R3, Banerjee D4.
Author information
1Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India; Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India.
2Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India.
3Department of Biotechnology, Maharishi Markandeshwar University, Mullana, Ambala 133207, India.
4Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India. Electronic address: [email protected].
Journal
Med Hypotheses. 2015 Jan 10. pii: S0306-9877(15)00005-5. doi: 10.1016/j.mehy.2014.12.022. [Epub ahead of print]
Affiliation
Abstract
Tuberculosis is continuing as a problem of mankind. With evolution, MDR and XDR forms of tuberculosis have emerged from drug sensitive strain. MDR and XDR strains are resistant to most of the antibiotics, making the management more difficult. BCG vaccine is not providing complete protection against tuberculosis. Therefore new infections are spreading at a tremendous rate. At the present moment there is experimental evidence to believe that Vitamin A and Vitamin D has anti-mycobacterial property. It is in this context, we have hypothesized a host based approach using the above vitamins that can cause possible prevention and cure of tuberculosis with minimal chance of resistance or toxicity.
Copyright © 2015 Elsevier Ltd. All rights reserved.
PMID
SOURCE:
25617043 [PubMed - as supplied by publisher]
Elsevier Science: Full text
http://www.ncbi.nlm.nih.gov/m/pubmed/25617043/

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