(21-03-15) No association between allergy and current 25-hydroxy vitamin D in serum or vitamin D

intake; Barman M, Jonsson K, Hesselmar B, Wold A, Sandberg

A, Sandin A; (Jan 2015)

AIM Vitamin D may be involved in allergy development, but there is conflicting evidence. We investigated if dietary intake of vitamin D and levels of 25OHD in serum differed between allergic and non-allergic adolescents and if serum 25OHD correlated with dietary intake of vitamin D or season of blood sampling.
METHODS Serum 25-hydroxy vitamin D (25OHD) levels were analysed in 13-year-old subjects with atopic eczema (n=55), respiratory allergy (n=55) or no allergy (n=55). Intake of fat-containing foods was assessed by food frequency questionnaires and total daily vitamin D intake was calculated. Logistic regression was used to adjust for gender, parental allergy and time of blood sampling.
RESULTS Subjects with atopic eczema or respiratory allergy did not differ from non-allergic controls regarding serum 25OHD levels or calculated vitamin D intake. Subjects sampled in the autumn had significantly higher levels of serum 25OHD than subjects sampled in the winter or spring. Serum 25OHD levels correlated to consumption of vitamin D fortified lean milk (p=0.001).
CONCLUSION The findings suggest no association between allergy and 25OHD levels in serum or vitamin D intake in adolescents. Serum 25OHD levels correlated to intake of vitamin D fortified lean milk. This article is protected by copyright. All rights reserved.

Source: Acta Pædiatrica  |  Posted 3 weeks ago

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