(27-11-06) Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.

Malavazos AE, Ermetici F, Coman C, Corsi MM, Morricone L, Ambrosi B.
Endocrinology Unit, Department of Medical and Surgical Sciences, University of Milano, IRCCS Policlinico San Donato, Via Morandi 30, I-20097, San Donato Milanese (MI), Italy.

Adipocytokine levels and visceral adipose tissue (VAT) seem to be associated with some cardiac abnormalities and a role of visceral fat in predisposing to cardiac dysfunction, possibly through a low-grade state of inflammation, has been demonstrated. In this study we firstly show that elevated levels of both monocyte chemoattractant protein 1 (MCP-1) and soluble IL-6 receptor/interleukin-6 (sIL-6R/IL-6) complex are closely correlated with epicardial fat thickness.

Source: Int J Cardiol.

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