(10-06-2017) Anti-inflammatory activities of triterpene lactones from Lactuca sativa

Article ·

Abstract
Lactuca sativa (lettuce) is a famous vegetable which is also used traditionally for management of inflammatory conditions. Aim of the study was to isolate and identify potential bioactive compounds that might be involved anti-inflammatory activity of Lactuca sativa. 3,14-Dihydroxy-11,13-dihydrocostunolide (compound 1) and 8-Tigloyl-15-Deoxyl-actucin (compound 2) were isolated from extract of Lactuca sativa. Both compounds showed substantial lipoxygenase inhibitory activity. Similarly, the isolated compounds revealed significant (p<0.05) in-vivo anti-inflammatory activity based on carrageenan induced paw edema model. Significant results of the isolated compounds indicate their considerable potential to be further studied at molecular and cellular level.

Anti-inflammatory activities of triterpene lactones from Lactuca sativa. Available from: Source: https://www.researchgate.net/publication/228480415_Anti-inflammatory_activities_of_triterpene_lactones_from_Lactuca_sativa [accessed May 22, 2017].

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In evidenza

"L'informazione presente nel sito serve a migliorare, e non a sostituire, il rapporto medico-paziente."

Per coloro che hanno problemi di salute si consiglia di consultare sempre il proprio medico curante.