(26-06-07) Effects of a short-term intervention with a paleolithic diet in healthy volunteers.

Osterdahl M, Kocturk T, Koochek A, Wandell PE.
1Department of Neurobiology, Center for Family and Community Medicine, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Objectives:Prevention of cardiovascular diseases by paleolithic or hunterer-gatherer diets has been discussed during recent years.Methods:Our aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study. Complete dietary assessment was available for six subjects.Results:Mean weight decreased by 2.3 kg (P<0.001), body mass index by 0.8 (P<0.001), waist circumference by 0.5 cm (P=0.001), systolic blood pressure by 3 mm Hg (P=0.03) and plasminogen activator inhibitor-1 by 72% (P=0.020). Regarding nutrient intake, intake of energy decreased by 36%, and other effects were also observed, both favourable (fat composition, antioxidants, potassium-sodium rate) and unfavourable (calcium).Conclusion:This short-term intervention showed some favourable effects by the diet, but further studies, including control group, are needed.European Journal of Clinical Nutrition advance online publication, 16 May 2007; doi:10.1038/sj.ejcn.1602790.

Fonte: Eur J Clin Nutr

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