(28-04-08) Centrally-Located Body Fat is Related to Appetitive Hormones in Healthy Postmenopausal Women.

Ritland L, Alekel D, Matvienko O, Hanson K, Stewart J, Hanson L, Reddy M, Van Loan M, Genschel U.

L Ritland, Food Science and Human Nutrition, Iowa State University, Ames, United States.

Objective: Body composition and energy homeostasis are thought to affect the appetitive hormones: adiponectin, leptin, insulin, and ghrelin. This study examined whether centrally-located fat and/or overall adiposity were related to these appetitive hormones in healthy postmenopausal women. Design: Overall and regional body composition was assessed by dual-energy X-ray absorptiometry in relation to plasma adiponectin, serum leptin, serum insulin, and plasma ghrelin in 242 postmenopausal women. Results: Regression analyses revealed that the androidal-to-gynoidal fat mass ratio (18.0%), age (3.2%), and white blood cell count (1.8%) accounted for 28% of the variability in adiponectin (F=22.2; P
Source: Eur J Endocrinol. 2008 Apr 7

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