(03-03-06) Adipose tissue and cytokines.
Trotti R, Cestaro B, Cazzola R, Ferrari E, Rondanelli M.
Laboratorio di Analisi Chimico-cliniche, IRCCS Fondazione <
Adipose tissue is not simply a storage depot for excessed energy intake, it is also able to produce and release several substances with local (autocrine) and systemic (endocrine) actions. An up-to-date review of our knowledge in this area is given here. Several of the compounds deriving from adipose tissue have been shown to play a role in obesity-related health complications. The production of cytokines, such as Tumor Necrosis Factor-alpha (TNF-alpha), IL-6, and leptin, is implicated in the development of several disorders. Insulin resistance is one of the most clinically significant.
Minerva Gastroenterol Dietol. 2001 Dec;47(4):205-207.
PMID: 16493379 [PubMed - as supplied by publisher]
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