(16-06-10) The Mediterranean diet contributes to the preservation of left ventricular systolic function and
The Mediterranean diet contributes to the preservation of left ventricular systolic function andto the long-term favorable prognosis
of patients who have had anacute coronary event.
Chrysohoou C, Panagiotakos DB, Aggelopoulos P, Kastorini CM, Kehagia I,
Pitsavos C, Stefanadis C.
First Cardiology Clinic School of Medicine University of Athens Greece.
Abstract
BACKGROUND: The effect of the cardioprotective Mediterranean diet on the
development of cardiac abnormalities and prognosis of cardiac patients has
rarely been investigated. OBJECTIVE: We sought to evaluate the relation between
the Mediterranean diet, the development of left ventricular systolic
dysfunction (LVSD) at hospitalization, and the 2-y prognosis of patients who
have had an acute coronary syndrome (ACS). DESIGN: During 2006-2009, 1000
consecutive patients with ACS were enrolled; of these patients, 459 had LVSD
(ejection fraction <40%) at hospitalization [367 men with a mean (+/-SD) age of
64 +/- 14 y, and 92 women aged 71 +/- 12 y], whereas 541 had preserved left
ventricular systolic function (421 men aged 62 +/- 12 y, and 120 women aged 67
+/- 12 y). Adherence to the Mediterranean diet was assessed by the validated
Mediterranean Diet Score (MedDietScore; theoretical range: 0-55). RESULTS: The
MedDietScore was associated with less likelihood of developing LVSD at
hospitalization [odds ratio (OR) per 1/55 unit: 0.93; 95% CI: 0.88, 0.99; P =
0.04], less likelihood of remodeling (ie, ejection fraction <50% at 3 mo follow-
up; OR: 0.90; 95% CI: 0.78, 1.03: P = 0.06), and less likelihood of recurrent
cardiovascular disease events during the 2 y of follow-up (OR: 0.88; 95% CI:
0.80, 0.98; P = 0.04), after adjustment for various confounders. CONCLUSIONS:
Greater adherence to the Mediterranean diet seems to preserve left ventricular
systolic function and is associated with better long-term prognosis of patients
who have had an ACS.
Source: Am J Clin Nutr. 2010 May 19. [Epub ahead of print]
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Informazioni utili
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Ricette a zona
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Tabelle nutrizionali
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Tabella composizione corporea
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ABC della nutrizione
