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Le ricerche di Gerona 2005

(26-08-10) A randomized clinical trial of home-based exercise combined with a slight caloric restriction on obesity prevention among women.





Mediano MF, Barbosa JS, Moura AS, Willett WC, Sichieri R.
Applied Physiology to Physical Education Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil; Department of Clinical and Experimental Medicine, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Abstract
OBJECTIVE: The study investigated the effectiveness of home-based exercise combined with a slight caloric restriction on weight change during 12months in non obese women. METHODS: A randomized clinical trial with a factorial design was conducted from 2003 to 2005. Two hundred three middle-aged women (Rio de Janeiro/Brazil), 25-45years, were randomly assigned to one of two groups: control (CG) and home-based exercise (HB). The HB group received a booklet on aerobic exercise that could be practiced at home (3 times/week - 40min/session), in low-moderate intensity, during 12months. Both groups received dietary counseling aimed at a slight energy restriction of 100-300 calories per day. RESULTS: The HB experienced a greater weight loss in the first 6months (-1.4 vs. -0.8kg; p=0.04), but after 12months there was no differences between groups (-1.1 vs. -1.0; p=0.20). Of the serum biochemical markers, HDL-cholesterol showed major change, with an increase at month 12 of 18.3mg/dl in the HB compared to 9.5 in the CG (p<0.01). CONCLUSION: Home-based exercise promoted greater weight reduction during the first six months after which no further benefits are observed. Continuous favorable changes in HDL-cholesterol after 1year suggest that home-based exercise promote health benefits. Copyright ? 2010. Published by Elsevier Inc.

Source : Prev Med. 2010 Jul 20. [

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