(21-01-11) Effects of meals with different glycaemic index on postprandial blood glucose

1 response in patients with Type diabetes treated with continuous subcutaneous
insulin infusion.
Parillo M, Annuzzi G, Rivellese AA, Bozzetto L, Alessandrini R, Riccardi G,
Capaldo B.

AORN S. Anna S. Sebastiano Hospital, Caserta Department of Clinical and
Experimental Medicine, Federico II University, Napoli, Italy.
Abstract
To Diabet. Med. 28, 227-229 (2011) ABSTRACT: Objective evaluate the impact of
high-glycaemic index and low-glycaemic index meals on postprandial blood
1 diabetes treated with glucose in patients with Type continuous subcutaneous
Sixteen patients with insulin infusion. Methods 1 diabetes under Type
continuous subcutaneous insulin infusion treatment,  ? years (mean 0.5 ? age 36
mmol/mol), 1.1 ? 0.2% (56 ? sem), HbA(1c) 7.6 consumed two test meals with an
identical macronutrient composition, but with a different glycaemic index: 59
vs. 90. Blood glucose was checked min before the test meal and every 30
min. The same thereafter for 180 preprandial insulin dose was administered on
 the two occasions. Results Blood glucose concentrations following the low-
glycaemic index meal were significantly lower than those of the high-glycaemic
 index meal (P<0.05   to P<0.01). The blood glucose area under the curve after 
the low-glycaemic index meal was 20% lower than after the high-glycaemic meal
Our data show that meals with the same 0.006). Conclusions = (P carbohydrate
content but a different glycaemic index produce clinically significant
differences in postprandial blood glucose.

Source:
Diabet Med. 2011 Feb;28(2):227-9. doi: 10.1111/j.1464-5491.2010.03176.x.
2011 The Authors. Diabetic Medicine ? 2011 Diabetes UK.

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