(10-05-11) Effects of Exercise on Cardiovascular Risk Factors in Type 2 Diabetes: A meta-analysis.

Chudyk A, Petrella RJ.
Source
Corresponding author: Robert J. Petrella, [email protected].
Abstract
OBJECTIVE Exercise is a cornerstone of diabetes management and the prevention
of incident diabetes. However, the impact of the mode of exercise on
cardiovascular (CV) risk factors in type 2 diabetes is unclear. RESEARCH DESIGN
AND METHODS We conducted a systematic review of the literature between 1970 and
October 2009 in representative databases for the effect of aerobic or
resistance exercise training on clinical markers of CV risk, including glycemic
control, dyslipidemia, blood pressure, and body composition in patients with
type 2 diabetes. RESULTS Of 645 articles retrieved, 34 met our inclusion
criteria; most investigated aerobic exercise alone, and 10 reported combined
exercise training. Aerobic alone or combined with resistance training (RT)
significantly improved HbA(1c) -0.6 and -0.67%, respectively (95% CI -0.98 to
-0.27 and -0.93 to -0.40, respectively), systolic blood pressure (SBP) -6.08
and -3.59 mmHg, respectively (95% CI -10.79 to -1.36 and -6.93 to -0.24,
respectively), and triglycerides -0.3 mmol/L (95% CI -0.48 to -0.11 and -0.57
to -0.02, respectively). Waist circumference was significantly improved -3.1 cm
(95% CI -10.3 to -1.2) with combined aerobic and resistance exercise, although
fewer studies and more heterogeneity of the responses were observed in the
latter two markers. Resistance exercise alone or combined with any other form
of exercise was not found to have any significant effect on CV markers.
CONCLUSIONS Aerobic exercise alone or combined with RT improves glycemic
control, SBP, triglycerides, and waist circumference. The impact of resistance
exercise alone on CV risk markers in type 2 diabetes remains unclear.

Source: Diabetes Care. 2011 May;34(5):1228-37.

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