(15-06-11) Impact of hip circumference and height on incident diabetes: results from 6-year follow-up in the Tehran Lipid and Glucose Study.

Bozorgmanesh M, Hadaegh F, Zabetian A, Azizi F.
Source
Prevention of Metabolic Disorders Research Center Endocrine Research Center,
Research Institute for Endocrine Sciences, Shahid Beheshti University of
Medical Sciences, Tehran, Iran.
Abstract
To Aim: investigate the effects of height and hip circumference, individually
and in A combination with waist circumference, on incident diabetes. Methods:
total of 1589 men and 2132 women, free of diabetes at baseline aged years 20 ??
participated in a 6-year follow-up examination. The standard 2-h post-challenge
plasma glucose test was performed at baseline and during follow-up. The Cox
model was used to regress the hazard of diabetes on height and hip
circumference individually and in combination with waist circumference.
Median follow-up was 6 years, with a total of 9433 Results: 607 person- and 12
years follow-up among men and women, respectively. The incidence rate of
CIs) was 9.0 (7.6-11.5) and 11.0 (9.6--13.4) diabetes (95% persons per per 1000
year in men and women, respectively. Among men, after multiple adjustments, the
anthropometric measures were no longer associated with incident diabetes. Among
CIs) women, the age-adjusted hazard ratio (95% of diabetes was 0.80 (0.61-1.04)
for height, 1.39 (1.21-1.60) for hip circumference and 1.86 (1.59-2.17) for
waist circumference. After further adjustment for waist circumference, the
hazard ratios were 0.69 (0.53-0.90) for height and 0.76 (0.61-0.96) for hip
circumference. These inverse associations resisted multiple adjustments. The
hazard ratio for waist circumference increased by 7 and 54% when height and hip
circumference were We observed that height included in the models. Conclusion:
and hip circumference were inversely associated with incident diabetes among
women and that these associations could be explored by considering the effect
of waist circumference. The risk of diabetes attributable to waist
circumference might be underestimated were the effects of height and hip
circumference not considered.

Source: Diabet Med. 2011 May 31. doi: 10.1111/j.1464-5491.2011.03343.x. [Epub ahead of print]

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