(02-07-11) Poor Glycemic Control Linked to Heart Failure in Patients with Type 1 Diabetes

Patients with type 1 diabetes who have poor glycemic control are at increased risk for heart failure, according to an industry-funded study in the Lancet.
Using Swedish health registries, researchers identified some 21,000 adults with type 1 diabetes (mean age, 39). During a median 9 years' follow-up, 3% of the patients experienced heart failure.
After multivariable adjustment, patients with a hemoglobin A1c level of 10.5% or above were more likely to develop heart failure, compared with those with a level below 6.5% (hazard ratio, 3.98). Each 1% increase in HbA1c was associated with a 30% increase in heart failure risk.
A commentator writes that the key message from this paper is that "tight control of glycemia in type 1 diabetes is essential." But for type 2 diabetes, he adds, "the emphasis ... should remain on tight control of lipids and blood pressure, with reasonable but not exaggerated efforts to control glycemia."

Source: Lancet article (Free abstract)

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