(05-11-11) Fruit and vegetable intake and cognitive function in the SU.VI.MAX 2 prospective study

1,2,3
1. Sandrine P?neau,
2. Pilar Galan,
3. Claude Jeandel,
4. Monique Ferry,
5. Valentina Andreeva,
6. Serge Hercberg,
7. Emmanuelle Kesse-Guyot, and
8. the SU.VI.MAX 2 Research Group
+ Author Affiliations
1. 1From Centre de G?rontologie, Clinique Antonin Balmes, CHU Montpellier Universit? I, Montpellier, France (SP and CJ); Unit? de Recherche en Epid?miologie Nutritionnelle, U557 INSERM/U1125 Inra/Cnam/Universit? Paris 13, CRNH IdF, Bobigny, France (SP, PG, CJ, MF, VA, SH, and EK-G); Unit? de Surveillance et d'Epid?miologie Nutritionnelle, Institut de Veille Sanitaire, Universit? Paris 13, Bobigny, France (SH); and D?partement de Sant? Publique, H?pital Avicenne, Bobigny, France (SH).
+ Author Notes
? ↵2 Supported by the Agence Nationale de la Recherche (ANR-05-PNRA-010), Direction G?n?rale de la Sant? (Ministry of Health), M?d?ric, Sodexo, Ipsen, Mutuelle G?n?rale de l'Education Nationale (MGEN), and Pierre Fabre. (Mederic and MGEN are French health insurance organizations complementary to the national health insurance system. Ipsen and Pierre Fabre are private pharmaceutical companies. Sodexo is a food-catering company that sponsored events between the researchers and study participants.)
? ↵3 Address correspondence to S P?neau, UMR Inserm/Inra/Cnam/Univ Paris 13, CRNH Ile-de-France, SMBH Paris 13, 74 rue Marcel Cachin, 93017 Bobigny Cedex, France. E-mail: [email protected].
Abstract
Background: Current hypotheses suggest that intake of fruit and vegetables (FVs) protects against age-related cognitive impairment.
Objective: We examined the 13-y association between FV intake and cognitive performance in a sample of French adults.
Design: A total of 2533 subjects aged 45?60 y at baseline, who were part of the Supplementation with Antioxidant Vitamins and Minerals 2 (SU.VI.MAX 2) cohort, were selected. FV intake was estimated at baseline in participants who had completed at least six 24-h dietary records. Cognitive performance was assessed 13 y after baseline and included an evaluation of verbal memory (RI-48 cued recall, semantic, and phonemic fluency tests) and executive function (trail-making and forward and backward digit span tests). Principal components analysis was performed to account for correlations in test scores. The relation between cognitive performance and quartiles of FV intake was assessed by multivariate linear regression analyses.
Results: Intakes of FVs (P-trend = 0.02), fruit alone (P-trend = 0.04), vitamin C?rich FVs (P-trend = 0.03), vitamin C (P-trend = 0.005), and vitamin E (P-trend = 0.04) were positively associated with verbal memory scores. In contrast, intakes of FVs (P-trend = 0.006), vegetables alone (P-trend = 0.03), and β-carotene?rich FVs (P-trend = 0.02) were negatively associated with executive functioning scores.
Conclusions: FVs might have a differential effect on cognition according to groups of FVs and type of cognitive function. Further research using sensitive and reliable measures of various types of cognitive function is needed to clarify the effect of individual FV groups and nutrients.

Source: Am J Clin Nutr November 2011 vol. 94 no. 5 1295-1303

News

---

In evidenza

"L'informazione presente nel sito serve a migliorare, e non a sostituire, il rapporto medico-paziente."

Per coloro che hanno problemi di salute si consiglia di consultare sempre il proprio medico curante.