(28-11-11) Cocoa antioxidants and cardiovascular health

Carl L Keen, Roberta R Holt, Patricia I Oteiza, C?sar G Fraga, and Harold H Schmitz



ABSTRACT
An increasing body of epidemiologic evidence supports the concept that diets rich in fruits and vegetables can promote health and attenu- ate, or delay, the onset of various diseases. Epidemiologic data support the idea that these health benefits are causally linked to the consumption of certain flavonoids present in fruit and vegetables. In the context of cardiovascular health, a particular group of flavonoids, namely, the flavan-3-ols (flavanols), has received attention. Flavanol-rich, plant- derived foods and beverages include wine, tea, and various fruits and berries, as well as cocoa and cocoa products. Numerous dietary inter- vention studies in humans and animals indicate that flavanol-rich foods and beverages might exert cardioprotective effects with respect to vas- cular function and platelet reactivity. This review discusses the bioac- tivity of flavanols in the context of cardiovascular health, with respect to their bioavailability, their antioxidant properties, and their vascular effects.

Source: Am J Clin Nutr 2005;81(suppl):298S?303S.

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