(18-03-12) Exercise Therapy in Type 2 Diabetes: Is daily exercise required to optimize glycemic control?

van Dijk JW, Tummers K, Stehouwer CD, Hartgens F, van Loon LJ.
Source
Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology
and Metabolism, Maastricht University Medical Centre+, Maastricht, the
Netherlands.
Abstract
OBJECTIVEGiven the transient nature of exercise-induced improvements in
insulin sensitivity, it has been speculated that daily exercise is preferred to
maximize the benefits of exercise for glycemic control. The current study
investigates the impact of daily exercise versus exercise performed every other
day on glycemic control in type 2 diabetic patients.RESEARCH DESIGN AND
METHODSThirty type 2 diabetic patients (age 60 ? 1 years, BMI 30.4 ? 0.7 kg/m
(2), and HbA(1c) 7.2 ? 0.2%) participated in a randomized crossover experiment.
Subjects were studied on three occasions for 3 days under strict dietary
standardization but otherwise free-living conditions. Blood glucose homeostasis
was assessed by continuous glucose monitoring over 48 h during which subjects
performed no exercise (control) or 60 min of cycling exercise (50% maximal
workload capacity) distributed either as a single session performed every other
day or as 30 min of exercise performed daily.RESULTSThe prevalence of
hyperglycemia (blood glucose >10 mmol/L) was reduced from 7:40 ? 1:00 h:min per
day (32 ? 4% of the time) to 5:46 ? 0:58 and 5:51 ? 0:47 h:min per day,
representing 24 ? 4 and 24 ? 3% of the time, when exercise was performed either
daily or every other day, respectively (P < 0.001 for both treatments). No
differences were observed between the impact of daily exercise and exercise
performed every other day.CONCLUSIONSA short 30-min session of moderate-
intensity endurance-type exercise substantially reduces the prevalence of
hyperglycemia throughout the subsequent day in type 2 diabetic patients. When
total work is being matched, daily exercise does not further improve daily
glycemia compared with exercise performed every other day.
PMID: 22399700 [PubMed - as supplied by publisher]

Source: Diabetes Care. 2012 Mar 7. [Epub ahead of print]

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