(07-05-12) Increasing incidence of pediatric inflammatory bowel disease in Spain (1996-2009): The SPIRIT registry.

Mart?n-de-Carpi J, Rodr?guez A, Ramos E, Jim?nez S, Mart?nez-G?mez MJ, Medina
E; on behalf of the SPIRIT-IBD Working Group of SEGHNP (Sociedad Espa?ola de
Gastroenterolog?a, Hepatolog?a y Nutrici?n Pedi?trica).
Source
Unidad para el Cuidado Integral de la Enfermedad Inflamatoria Intestinal
Pedi?trica, Secci?n de Gastroenterolog?a, Hepatolog?a y Nutrici?n Pedi?trica,
Hospital Sant Joan de D?u, Barcelona. [email protected].
Abstract
BACKGROUND:
Although pediatric inflammatory bowel disease (IBD) diagnosis has increased in
the last decades in Spain, there are no consistent epidemiologic data. Our aim
was to describe the changing pattern of pediatric IBD incidence in Spain in the
last 14 years.
METHODS:
A retrospective survey of patients diagnosed below 18 years of age in the
period 1996-2009 was performed. Patients' data were obtained from the
hospitals' databases. To avoid reduced accrual of cases diagnosed by adult
physicians, adult IBD units in referral centers were invited to participate.
Seventy-eight centers participated in our survey. Rates of incidence were
calculated using age-stratified population-based epidemiologic data. Incidence
rates were compared for the last 14 years (1996-2009).
RESULTS:
In total, data from 2107 patients were obtained: 1,165 Crohn's disease (CD,
55.3%), 788 ulcerative colitis (UC, 37.4%), and 154 IBD unclassified. The sex
distribution was 56.4% male, with higher predominance for CD (59.3%) as
compared to UC (52.8%) and IBD unclassified (53.2%) (P = 0.012). The median age
at diagnosis was 12.3 years (p25-75 9.7-14.6) with significant differences
between diseases. IBD incidence increased from 0.97 to 2.8/100,000 inhabitants
<18 years/year in the study period. Although this increase is more evident for
CD (from 0.53 to 1.7), UC has also risen considerably (0.39 to 0.88).
CONCLUSIONS:
This is the first attempt to calculate the current incidence of pediatric IBD
in Spain. A significant increase of incidence rates in the study period was
observed. In the last 14 years pediatric IBD incidence has almost tripled, with
a more important CD increase. (Inflamm Bowel Dis 2012;).

Source: Inflamm Bowel Dis. 2012 Apr 25. doi: 10.1002/ibd.22980. [Epub ahead of print]

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