(11-06-12) Alcohol 2 diabetes and autoimmune consumption is associated with reduced risk of Type diabetes in adults:

results from the Nord-Tr?ndelag health study.

Rasouli B, Ahlbom A, Andersson T, Grill V, Midthjell K, Olsson L, Carlsson S.
Source
Department of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden NTNU Institute of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, and Trondheim University Hospital, Trondheim HUNT Research Centre, Department of Community Medicine and General Practice, Norwegian University of Science and Technology, Levanger, Norway.
Abstract
 Aims We investigated the influence of different aspects of alcohol consumption on the We used data 2 diabetes and autoimmune diabetes in adults. Methods risk of Type from the Nord-Tr?ndelag Health Survey (HUNT) study, in which all adults aged years from Nord-Trondelag County were invited to participate in three 20 ≥ surveys in 1984-1986, 1995-1997 and 2006-2008. Patients with diabetes were years were 35 identified using self-reports, and participants with onset age ≥ 2 diabetes if they were negative for anti-glutamic classified as having Type 1841) and as having autoimmune diabetes if they were = acid decarboxylase (n 140). Hazard ratios of amount = positive for anti-glutamic acid decarboxylase (n and frequency of alcohol use, alcoholic beverage choice, and binge drinking and Moderate alcohol consumption alcohol use disorders were estimated. Results 2 diabetes (adjusted for confounders) was associated with a reduced risk of Type CI g/day 0.48, 95% in men, but not in women (hazard ratio for men 10-15 CI 0.33-1.96). The g/day 0.81, 95% 10 0.28-0.77; hazard ratio for women ≥ reduced risk was primarily linked to consumption of wine [hazard ratio 0.93, CI 0.87-0.99 (per g/day)]. No increased risk wa 95%s seen in participants reporting binge drinking or in problem drinkers. The results were also compatible with a reduced risk of autoimmune diabetes associated with alcohol CI 0.45-1.08 (frequent consumption) and consumption [hazard ratio 0.70, 95% Moderate alcohol g/day)]. Conclusions CI 0.13-0.97 (2-7 hazard ratio 0.36, 95% 2 diabetes and autoimmune consumption associates with reduced risk of both Type diabetes. A protective effect of alcohol intake may be limited to men. High alcohol consumption does not seem to carry an increased risk of diabetes. ? 2012 The Authors. Diabetic Medicine ? 2012 Diabetes UK.
? 2012 The Authors. Diabetic Medicine ? 2012 Diabetes UK.

Source: Diabet Med. 2012 May 22. doi: 10.1111/j.1464-5491.2012.03713.x. [Epub ahead of print]

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