(27-06-12) Femoral-gluteal 1 diabetes adiposity is not associated with insulin sensitivity in Type

Shay CM, Secrest AM, Miller RG, Strotmeyer ES, Goodpaster BH, Kelsey SF, Orchard TJ.
Source
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA Department of Biostatistics and Epidemiology, University of Oklahoma Health Science Center, Oklahoma City, OK Department of Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Abstract
 Aims To quantify and compare associations between femoral-gluteal adiposity and 1 diabetes mellitus with adults with insulin sensitivity in adults with Type 28) = 1 diabetes (n  Individuals with Type normal glucose tolerance. Methods were recruited from the Pittsburgh Epidemiology of Diabetes Complication study, a 24-year prospective study of childhood-onset diabetes, and compared 56) of = cross-sectionally with individuals with normal glucose tolerance (n similar age, sex and BMI. Insulin sensitivity was defined as whole-body glucose disposal measured by hyperinsulinaemic-euglycaemic clamps. Adiposity was 1  Individuals with Type quantified by dual energy X-ray absorptiometry. Results kg min(-1)  mg diabetes exhibited lower insulin sensitivity (5.8 vs. 8.2  fat-free mass(-1) , P
Source: Diabet Med. 2012 Jun 4. doi: 10.1111/j.1464-5491.2012.03728.x. [Epub ahead of print]

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