(29-09-12) Increased dietary fruit intake was associated with lower burden of carotid 2 diabetes atherosclerosis in Chinese patients with Type

Increased dietary fruit intake was associated with lower burden of carotid 2 diabetes atherosclerosis in Chinese patients with Type mellitus.


Chan HT, Yiu KH, Wong CY, Li SW, Tam S, Tse HF.
Source
Cardiology Division, Department of Medicine, the University of Hong Kong,
Queen Mary Hospital, Hong Kong Department of Medicine, Tung Wah Hospital, Hong
Kong Department of Clinical Biochemistry Unit, Queen Mary Hospital, Hong Kong
Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty
of Medicine, the University of Hong Kong, Hong Kong SAR, China.
Abstract
Previous studies demonstrated that Background: high fruit consumption was
associated with a lower risk of cardiovascular 2 events in patients with Type
diabetes mellitus. However, the relationship between fruit intake and carotid
atherosclerosis in these patients is unknown. We studied the relationship
between dietary fruit intake and carotid intima-media thickness in patients
A 2 diabetes. Methods: with Type 2 total of 255 Chinese patients with Type
diabetes were recruited. Dietary fruit intake was assessed by a validated food-
frequency questionnaire, and carotid intima-media thickness was measured by
high-resolution Among patients with three different ultrasonography. Results:
tertiles of g/day), 39.7 ? 7.1 vs. 92.6 ? 8.6 vs. 41.5 ? fruit intake (14.5
there was no  difference in their clinical characteristics (all P>0.05). 
Patients with the highest tertile of fruit intake had a significantly higher
BMI and diastolic blood pressure than those with the lowest tertile intake.
Furthermore, serum high-sensitivity C-reactive protein, 8-isoprostane and
superoxide dismutase were similar among the three tertiles of patients (all  P> 
0.05). However, patients with the highest tertile of fruit intake had lower
mm, 0.03 ? 0.02 vs. 1.08 ? carotid intima-media thickness (0.97 0.046) and = P
0.022) = prevalence of carotid plaque (11.76 vs. 1.18%, P than those with the
lowest tertile of fruit intake. Multivariate regression analysis revealed the
-0.086, = highest tertile of fruit intake (? 0.049) was independently = P
associated with carotid intima-media thickness. Our results Conclusions:
2 demonstrated that, in Chinese patients with Type diabetes, higher dietary
fruit intake was associated with a lower burden of carotid atherosclerosis as
reflected by lower carotid intima-media thickness and prevalence of carotid plaque.

Source: Diabet Med. 2012 Aug 22. doi: 10.1111/j.1464-5491.2012.03764.x. [Epub ahead of print]

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