(07-11-12) Research shows ginger selectively kills breast cancer cells

by David Gutierrez, staff writer

(NaturalNews) Ginger extract may turn out to be more effective at fighting
breast cancer than any drug currently on the market - so suggest the findings
of a new study conducted by researchers from the Biological Sciences
Department, Faculty of Sciences, King Abdulaziz University, Saudi Arabia, and
published in the Journal of Biomedicine and Biotechnology.

In their paper, the researchers note that in spite of the high global toll of
breast cancer, conventional drug therapies are of only middling effectiveness,
often with serious side effects.

"Despite significant advances toward targeted therapy and screening
techniques, breast cancer continues to be a chronic medical problem worldwide,
being the most common type of cancer in women and the leading cause of death,"
they write.

"Typically, the treatment of breast cancer involves hormonal therapy with ...
selective estrogen receptor (ER) modulators. However, almost all patients with
metastatic disease and approximately 40 percent of patients that receive [the
ER modulator] tamoxifen experience relapse that ends by death."

The researchers also note that ER antagonists have little to no effectiveness
against ER-negative breast cancer, and that the drugs may have such severe side
effects that their usefulness becomes limited. In addition, many breast cancer
cells are able to develop resistance to cancer drugs within the course of a
single treatment.

"Thus, identification of novel agents that are relatively safe but can
suppress growth of both ER-positive and ER-negative human breast cancers is
highly desirable," they write.

A safe, natural treatment?
The researchers exposed breast cancer cells in the laboratory to a crude
extract of ginger (Zingiber officinale). They found that ginger exhibited a
highly prized anti-cancer trait known as selective cytotoxicity: it inhibited
the reproduction of cancer cells while leaving healthy cells largely
unaffected. No conventional cancer treatment on the market exhibits this
property.

More specifically, ginger appeared to positively modulate a large number of
molecular anti-cancer mechanisms, including induction of programmed cell death
(apoptosis), up-regulation of the apoptosis gene Bax, down-regulation of
numerous ancer-associated genes and proteins, increased expression of cancer-
fighting proteins and inhibition of cancer-associated enzymes. Although the
researchers were not able to explain these molecular effects, the evidence in
their favor was striking.

"Ginger may be a promising candidate for the treatment of breast carcinomas,"
the researchers concluded.

Ginger - A medicinal powerhouse
If further studies bear out ginger's utility as a breast cancer treatment, it
could revolutionize the entire field of cancer medicine, since ginger extract
could easily be produced cheaply and in large quantities, and likely would have
few or no side effects.

Previous studies have already shown ginger to have a breast cancer-fighting
effect. More specifically, at least one study has shown that the ginger
compound [6]-Gingerol hampers metastasis in breast cancer. Other studies have
suggested that ginger extract or ginger components have the ability to fight
other cancers, including those of the colon or rectum, liver, lungs, pancreas,
prostate and skin (including melanoma).

Perhaps the findings should not be surprising. After all, ginger is one of the
oldest known medicinal foods. Probably originally cultivated in southern China,
ginber rapidly spread throughout Asia and the Spice Islands and from there,
eventually to West Africa, the Caribbean and India. Today it is widely consumed
as a food, spice and medicine in cultures across the world.

Scientific studies have linked ginger to no fewer than 100 different health
benefits - from its well-known anti-nausea and digestive-aid properties to anti-
microbial, anti-inflammatory and heart health-promoting effects.

Sources for this article include:
http://www.greenmedinfo.com/substance/ginger
http://www.naturalnews.com/026698_ginger_herb_Chi.html

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