(27-01-13) Differential associations between depressive symptoms and glycaemic control in outpatients with diabetes.

Bot M, Pouwer F, de Jonge P, Tack CJ, Geelhoed-Duijvestijn PH, Snoek FJ.
Source
CoRPS, Centre of Research on Psychology in Somatic diseases, Department of
Medical and Clinical Psychology, Tilburg University, Tilburg.
Abstract
AIMS:
Depression is common in people with diabetes, and related to higher HbA(1c)
levels. Depression, however, is a heterogeneous construct that involves a
variety of symptoms. As little is known about the associations of individual
depressive symptoms with HbA(1c) , we explored these associations in
outpatients with diabetes.
METHODS:
The study was conducted in three tertiary diabetes clinics in the Netherlands.
At baseline, the presence of the nine depressive symptoms that are listed in
the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition was
assessed with the nine-item Patient Health Questionnaire (PHQ-9). At baseline
and after a 1-year follow-up, HbA(1c) was derived from the medical charts.
RESULTS:
A total of 288 out of 646 subjects with diabetes (45%) reported one or more
depressive symptom(s). Depressed mood (? = 0.11, P = 0.005), sleeping
difficulties (? = 0.16, P < 0.001), appetite problems (? = 0.15, P < 0.001) and
suicidal ideation (? = 0.14, P = 0.001) were significantly related to higher
baseline HbA(1c) values. Furthermore, depressed mood (? = 0.09, P = 0.03)
sleeping difficulties (? = 0.12, P = 0.004), appetite problems (? = 0.11, P =
0.01) and psychomotor agitation/retardation (? = 0.09, P = 0.04) were
significantly related to higher HbA(1c) values at 1-year follow-up.
Associations were more pronounced in Type 1 diabetes than in Type 2 diabetes.
None of the depressive symptoms were related to change in HbA(1c) over time,
except suicidal ideation.
CONCLUSION:
In people with diabetes, several individual depressive symptoms were related
to higher HbA(1c) levels. These associations persisted over time. More research
is needed to investigate potential mechanistic pathways.

Source: Diabet Med. 2012 Nov 26. doi: 10.1111/dme.12082. [Epub ahead of print]


? 2012 The Authors.
Diabetic Medicine ? 2012 Diabetes UK

News

---

In evidenza

"L'informazione presente nel sito serve a migliorare, e non a sostituire, il rapporto medico-paziente."

Per coloro che hanno problemi di salute si consiglia di consultare sempre il proprio medico curante.